SCHEMBL1717809

SCHEMBL1717809

CC1(C)C2CC3CC(C2)CC1(O)C3

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.33
GRIN3B O60391 3/20 0.33
GRIN1 Q05586 3/20 0.33
GRIN2A Q12879 3/20 0.33
GRIN2B Q13224 3/20 0.33
GRIN2C Q14957 3/20 0.33
GRIN3A Q8TCU5 3/20 0.33
HSD11B1 P28845 3/20 0.33
SLC22A2 O15244 2/20 0.32
SLC47A1 Q96FL8 2/20 0.32
SLC22A1 O15245 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
STAT6 P42226 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL7082784 0.83 THRB (0.38) HSD11B1LMNA
Methacrylic Acid SCHEMBL7083287 0.83 HSD11B1 (0.35) HSD11B1
SCHEMBL4713608 0.80 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL811709 0.74 GRIN2D (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL546365 0.74 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11713092 0.73 HSD11B1 (0.36) HSD11B1
Water SCHEMBL27943536 0.72 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Bromide SCHEMBL28280728 0.72 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Ammonia Solution, Strong SCHEMBL3787685 0.72 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL20526370 0.70 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218720-A A kind of method for improving synthesis process of memantine 吴江信凯医药科技有限公司 2018-06-29 CN claimed
CN-105602311-A Waterproof agent for basements YANTAI SHUNLONG CHEMICAL TECH CO LTD 2016-05-25 CN claimed
US-4008251-A TRACTION FLUID ADDITIVES SUN OIL COMPANY, (SUN RESEARCH AND DEVELOPMENT CO.) 1977-02-15 US claimed
US-10781344-B2 Tackifier resin and pressure-sensitive adhesive composition HARIMA CHEMICALS, INCORPORATED (JP) 2020-09-22 US disclosed
US-20180371297-A1 TACKIFIER RESIN AND PRESSURE-SENSITIVE ADHESIVE COMPOSITION HARIMA CHEMICALS, INCORPORATED (JP) 2018-12-27 US disclosed
EP-3385351-A1 TACKIFIER RESIN AND PRESSURE-SENSITIVE ADHESIVE COMPOSITION Harima Chemicals, Incorporated (JP) 2018-10-10 EP disclosed
CN-108218720-A A kind of method for improving synthesis process of memantine 吴江信凯医药科技有限公司 2018-06-29 CN disclosed
CN-105602311-A Waterproof agent for basements YANTAI SHUNLONG CHEMICAL TECH CO LTD 2016-05-25 CN disclosed
CN-104936942-A Manufacturing process for memantine MITSUBISHI GAS CHEMICAL CO 2015-09-23 CN disclosed
CN-101389594-B Process for the preparation of adamantanamines HEXAL AG 2013-06-12 CN disclosed
EP-1820792-B1 Process for the preparation of adamantanamines HEXAL AG (DE) 2012-01-18 EP disclosed
WO-2007096124-A1 PROCESS FOR THE PREPARATION OF ADAMANTANAMINES HEXAL AG (DE) 2007-08-30 WO disclosed
EP-1820792-A1 Process for the preparation of adamantanamines HEXAL AG (DE) 2007-08-22 EP disclosed
US-6794528-B2 HEAT RESISTANCE, FLAME RETARDERS, STABILIZERS; REACTING DIALCOHOL COMPOUND WITH A PHOSPHYL OXYCHLORIDE COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-21 US disclosed
US-20030109736-A1 Phosphorus compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-12 US disclosed
EP-1277758-A1 PHOSPHORUS COMPOUND Daicel Chemical Industries, Ltd. (JP) 2003-01-22 EP disclosed
CN-1272105-A Compound containing six-membered rings, processes for their preparation, and their use as medicaments GILEAD SCIENCES INC (US) 2000-11-01 CN disclosed
US-4391823-A PESTICIDES RHONE-POULENC AGROCHIMIE (FR) 1983-07-05 US disclosed
US-4043927-A Friction or tractive drive containing ethers of adamantanes SUN VENTURES, INC. (US) 1977-08-23 US disclosed
US-4008251-A TRACTION FLUID ADDITIVES SUN OIL COMPANY, (SUN RESEARCH AND DEVELOPMENT CO.) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109736-A1 Phosphorus compound NR4A1, POLL, NR0B1 GRIN2D 2300/4885GRIN3B 2801/4885GRIN1 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.