Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20273044 | 0.82 | MGLL (0.35) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL16485405 | 0.81 | PTGS1 (0.36) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL20197866 | 0.79 | PTGS1 (0.40) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL22214489 | 0.79 | GBA1 (0.51) | HSP90AA1TLR9FAAHALDH1A1TP53 | |
| SCHEMBL21610368 | 0.79 | MGLL (0.59) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL19851854 | 0.79 | MGLL (0.59) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL19683934 | 0.77 | PTGS1 (0.35) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL19401650 | 0.77 | MGLL (0.57) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL12629192 | 0.76 | PTGS1 (0.56) | LMNASMN1; SMN2 | |
| SCHEMBL16856543 | 0.76 | MGLL (0.34) | HSP90AA1TLR9FAAHALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651411-B1 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| WO-2015155998-A1 | ANTI-HER3 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-15 | — | — | WO | disclosed |