Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197866 | 0.88 | PTGS1 (0.40) | PTGS1PTGS2HSP90AA1TLR9FAAH | |
| SCHEMBL12629192 | 0.81 | PTGS1 (0.56) | PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL26312049 | 0.81 | PTGS1 (0.56) | PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL22843961 | 0.81 | PTGS1 (0.32) | PTGS1PTGS2CA1CA2 | |
| SCHEMBL20273044 | 0.81 | MGLL (0.35) | PTGS1PTGS2HSP90AA1TLR9FAAH | |
| SCHEMBL24864496 | 0.80 | PTGS1 (0.39) | PTGS1PTGS2HSP90AA1TLR9FAAH | |
| SCHEMBL19901620 | 0.80 | PTGS1 (0.39) | PTGS1PTGS2HSP90AA1TLR9FAAH | |
| SCHEMBL20442394 | 0.79 | ALDH1A1 (0.37) | PTGS1PTGS2ALDH1A1HPGDMAPK1 | |
| SCHEMBL13752367 | 0.79 | PTGS1 (0.36) | PTGS1PTGS2HSP90AA1TLR9FAAH | |
| SCHEMBL22214489 | 0.78 | GBA1 (0.51) | PTGS1PTGS2HSP90AA1TLR9FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207540-A1 | ANTIBODY-DRUG-CONJUGATES COMPRISING NOVEL ANTHRACYCLINE-DERIVATIVES FOR CANCER TREATMENT | TOXINVENT OÜ (EE) | 2017-12-07 | — | — | WO | disclosed |