Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 6/20 | 0.52 |
| ▸ | CHRNG | P07510 | 6/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.52 |
| ▸ | CHRND | Q07001 | 6/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18515674 | 0.95 | QRFPR (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL16867578 | 0.95 | QRFPR (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL20880553 | 0.94 | CHRNB2 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515825 | 0.92 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18495169 | 0.91 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515734 | 0.91 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515559 | 0.91 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL16485401 | 0.88 | CHRNB2 (0.62) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL23790017 | 0.88 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL21320636 | 0.88 | CHRNB2 (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015155998-A1 | ANTI-HER3 ANTIBODY-DRUG CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-15 | — | — | WO | disclosed |