Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.47 |
| ▸ | CHRNG | P07510 | 2/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | CHRND | Q07001 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178196 | 0.94 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515674 | 0.90 | QRFPR (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL16867578 | 0.90 | QRFPR (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515825 | 0.89 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL26605054 | 0.87 | CTSS (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL5177591 | 0.87 | CTSS (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18515734 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL18495169 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL29385523 | 0.85 | CTSL (0.51) | CHRNA1CHRNGCHRNB1CHRNDCTSL | |
| SCHEMBL30805357 | 0.85 | CTSL (0.51) | CHRNA1CHRNGCHRNB1CHRNDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466976-A1 | ANTI-HER2 ANTIBODY-DRUG CONJUGATE | Daiichi Sankyo Company, Limited (JP) | 2019-04-10 | — | — | EP | disclosed |