Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718522 | 0.95 | KMT2A (0.67) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1718567 | 0.91 | KMT2A (0.65) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1717876 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1718708 | 0.84 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1719260 | 0.83 | KDM4E (0.69) | ALDH1A1NPSR1POLBMAPTKDM4E | |
| SCHEMBL1718144 | 0.83 | MAPT (0.64) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1717661 | 0.82 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1718178 | 0.82 | ALDH1A1 (0.80) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1719629 | 0.82 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1NPSR1ESR1 | |
| SCHEMBL1718368 | 0.81 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1NPSR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |