Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717837 | 0.91 | KMT2A (0.65) | KMT2AMEN1KDM4ELMNARAB9A | |
| SCHEMBL1718565 | 0.87 | MAPK1 (0.69) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL1718522 | 0.86 | KMT2A (0.67) | KMT2AMEN1KDM4ELMNARAB9A | |
| SCHEMBL1719737 | 0.86 | GAA (0.61) | KDM4ELMNAALDH1A1NPSR1MAPK1 | |
| SCHEMBL1719260 | 0.83 | KDM4E (0.69) | KDM4ELMNARAB9AALDH1A1NPSR1 | |
| SCHEMBL1720017 | 0.83 | MAPK1 (0.78) | KMT2AMEN1KDM4ELMNARAB9A | |
| SCHEMBL1718992 | 0.82 | USP2 (0.69) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL1718397 | 0.82 | USP2 (0.74) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL1717881 | 0.82 | KMT2A (0.61) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL1718370 | 0.81 | USP2 (0.59) | KMT2AMEN1KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |