Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 2/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17179336 | 0.84 | MGAM (0.34) | MGAMGAASIMGAM2AR | |
| SCHEMBL17179252 | 0.83 | AR (0.46) | MGAMGAASIMGAM2AR | |
| SCHEMBL17179352 | 0.77 | IDO1 (0.43) | MGAMGAASIMGAM2AR | |
| SCHEMBL17179329 | 0.77 | IMPDH2 (0.46) | — | |
| SCHEMBL17179439 | 0.77 | GRIN1 (0.40) | — | |
| SCHEMBL18421860 | 0.73 | OPRL1 (0.42) | — | |
| SCHEMBL17179333 | 0.72 | BCHE (0.33) | — | |
| SCHEMBL17179279 | 0.71 | BRPF1 (0.36) | AR | |
| SCHEMBL21420153 | 0.65 | IDO1 (0.47) | MGAMGAASIMGAM2AR | |
| SCHEMBL18418450 | 0.65 | IDO1 (0.47) | MGAMGAASIMGAM2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154169-A1 | BINDING FUNCTION3 (BF3) SITE COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-10-15 | — | — | WO | disclosed |