Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RHOC | P08134 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972781 | 0.79 | ALDH1A1 (0.63) | NPSR1RHOCRHOAALDH1A1POLB | |
| SCHEMBL3441354 | 0.79 | NPSR1 (0.56) | NPSR1RHOCRHOAALDH1A1POLB | |
| SCHEMBL3072529 | 0.76 | HRH3 (0.55) | NPSR1RHOCRHOAPOLBHDAC3 | |
| SCHEMBL1972320 | 0.75 | NPSR1 (0.68) | NPSR1RHOCRHOAALDH1A1POLB | |
| SCHEMBL13753178 | 0.75 | NPSR1 (0.64) | NPSR1ALDH1A1POLBHDAC3HDAC1 | |
| SCHEMBL30744927 | 0.74 | NPSR1 (0.61) | NPSR1ALDH1A1POLBPTGS1GAA | |
| SCHEMBL29646460 | 0.73 | GAA (0.68) | NPSR1ALDH1A1POLBHDAC3HDAC1 | |
| SCHEMBL1127884 | 0.73 | GAA (0.68) | NPSR1ALDH1A1POLBHDAC3HDAC1 | |
| SCHEMBL3885776 | 0.72 | NPSR1 (0.64) | NPSR1ALDH1A1POLBHDAC3HDAC1 | |
| SCHEMBL27790261 | 0.72 | CES2 (0.59) | NPSR1ALDH1A1POLBPTGS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428507-B1 | Cannabinoid receptor ligands | ABBVIE BAHAMAS LTD (BS) | 2015-10-21 | — | — | EP | disclosed |