Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744531 | 0.79 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK10 | |
| SCHEMBL4956852 | 0.75 | NPC1 (0.63) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL4749594 | 0.75 | SMN1; SMN2 (0.64) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL5483086 | 0.73 | HPGD (0.48) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK10 | |
| SCHEMBL15846889 | 0.73 | NPC1 (0.65) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL3579523 | 0.73 | NPC1 (0.65) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL2799189 | 0.72 | NPC1 (0.59) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL9410725 | 0.72 | NPC1 (0.59) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL538048 | 0.72 | NPC1 (0.63) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL8055595 | 0.70 | KMT2A (0.50) | HPGDSMN1; SMN2NPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-B1 | QUINOLONE DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2018-02-07 | — | — | EP | disclosed |
| CN-104903295-B | Carbostyril derivative | 卡迪拉保健有限公司 | 2017-09-01 | — | — | CN | disclosed |
| US-9394300-B2 | Quinolone derivatives | CADILA HEALTHCARE LIMITED (IN) | 2016-07-19 | — | — | US | disclosed |
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299193-A1 | NOVEL QUINOLONE DERIVATIVES | NQO2, UGT1A1, CYP11B2 | HPGD 346/4885SMN1; SMN2 3982/4885NPC1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.