Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.64 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.64 |
| ▸ | PRKACA | P17612 | 2/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.64 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.64 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.64 |
| ▸ | CIT | O14578 | 1/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | PRKCB | P05771 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.64 |
| ▸ | MARK3 | P27448 | 1/20 | 0.64 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.64 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.64 |
| ▸ | CLK1 | P49759 | 1/20 | 0.64 |
| ▸ | GSK3A | P49840 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465467 | 0.84 | ROCK2 (0.57) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL5463083 | 0.82 | ROCK2 (0.55) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL5470005 | 0.82 | ROCK2 (0.55) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL6559985 | 0.82 | ROCK2 (0.60) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL6558015 | 0.81 | ROCK2 (0.59) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL19557786 | 0.81 | ROCK2 (0.68) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| Hydrochloric Acid SCHEMBL8080144 | 0.81 | ROCK2 (0.44) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL4772895 | 0.80 | ROCK2 (0.67) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| SCHEMBL6560222 | 0.80 | ROCK2 (0.60) | ROCK2ROCK1PRKD3PRKACAPRKCQ | |
| Hydrochloric Acid SCHEMBL30976603 | 0.79 | ROCK2 (0.67) | ROCK2ROCK1PRKD3PRKACAPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150297679-A1 | METHODS AND ASSAYS RELATING TO MACROPHAGE DIFFERENTIATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297679-A1 | METHODS AND ASSAYS RELATING TO MACROPHAGE DIFFERENTIATION | MYADM, CD14, CD68 | ROCK2 2937/4885ROCK1 3491/4885PRKD3 2181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.