Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719212 | 0.91 | RXFP1 (0.62) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1719971 | 0.91 | PTGES (0.59) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1718772 | 0.90 | MAPT (0.61) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1719847 | 0.89 | MAPT (0.66) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1718513 | 0.87 | MAPT (0.64) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1718612 | 0.87 | MAPT (0.64) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1719273 | 0.87 | MAPT (0.62) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1719133 | 0.87 | MAPT (0.63) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1718851 | 0.86 | MAPT (0.68) | MAPTTHRBUSP2MAPK1RXFP1 | |
| SCHEMBL1718483 | 0.86 | MAPT (0.62) | MAPTTHRBUSP2MAPK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |