Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FASN | P49327 | 6/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17134928 | 0.91 | FASN (0.41) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17184249 | 0.91 | FASN (0.41) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17134927 | 0.90 | FASN (0.41) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17134767 | 0.87 | MAPT (0.43) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17134520 | 0.85 | MAPT (0.41) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17134725 | 0.84 | FASN (0.42) | MAPTFASNHSD11B1ALDH1A1CCR1 | |
| SCHEMBL17135227 | 0.84 | FASN (0.37) | MAPTFASNPRSS12HSD11B1ALDH1A1 | |
| SCHEMBL17134537 | 0.84 | PRSS12 (0.41) | MAPTFASNPRSS12ALDH1A1MGLL | |
| SCHEMBL17134614 | 0.84 | FASN (0.42) | MAPTFASNHSD11B1ALDH1A1CCR1 | |
| SCHEMBL17134984 | 0.83 | MAPT (0.43) | MAPTFASNPRSS12HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701689-B2 | Substituted pyridines and pyridazines as CCR10 receptor inhibitors | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-20150299214-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299214-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | ARG1, H1-0, TYR | PDE4A 2958/4885PDE4B 3655/4885PDE4C 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.