Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993507 | 0.93 | ADRA2B (0.32) | ADRA2B | |
| SCHEMBL13927595 | 0.87 | — | — | |
| SCHEMBL106446 | 0.82 | MET (0.40) | — | |
| SCHEMBL103259 | 0.78 | MET (0.41) | — | |
| SCHEMBL106882 | 0.77 | KDM1A (0.35) | — | |
| SCHEMBL12286388 | 0.75 | MST1R (0.39) | — | |
| SCHEMBL106586 | 0.72 | KDM1A (0.36) | — | |
| SCHEMBL10172437 | 0.72 | CCNB2 (0.35) | — | |
| SCHEMBL14230491 | 0.72 | MET (0.46) | ADRA2B | |
| SCHEMBL21383117 | 0.71 | MST1R (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426108-A1 | Processes and intermediates for preparing fused heterocyclic kinase inhibitors | MethylGene Inc. (CA) | 2012-03-07 | — | — | EP | disclosed |
| EP-2332536-A1 | Inhibitors of protein tyrosine kinase activity | MethylGene Inc. (CA) | 2011-06-15 | — | — | EP | disclosed |