SCHEMBL17185508

SCHEMBL17185508

O=S(=O)(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.54
CA1 P00915 13/20 0.50
MMP1 P03956 4/20 0.50
MMP2 P08253 4/20 0.50
MMP9 P14780 4/20 0.50
MMP8 P22894 4/20 0.50
MMP13 P45452 4/20 0.50
F2 P00734 4/20 0.45
PRSS1 P07477 4/20 0.45
PRSS2 P07478 4/20 0.45
PRSS3 P35030 4/20 0.45
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685584 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL22818194 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL1551243 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL1146134 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL2135574 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL169112 0.97 CA2 (0.50) CA2CA1MMP1MMP2MMP9
SCHEMBL1395645 0.88 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL1455645 0.88 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL17185511 0.84 CA2 (0.39) CA2CA1MMP1MMP2MMP9
SCHEMBL2135581 0.82 CA2 (0.50) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10876034-B1 Modified silicon dioxide material of fluorocarbon active agent type super-amphiphobic cutting-carrying agent suitable for water-based drilling fluid and preparation method thereof CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2020-12-29 US disclosed
CN-109337657-B Modified silicon dioxide material suitable for fluorocarbon active agent type super-amphiphobic chip carrying agent for water-based drilling fluid and preparation method and application thereof 中国石油大学(北京) 2020-04-24 CN disclosed
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME H1-0, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4 CA2 131/4885CA1 1693/4885MMP1 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.