Sugi Predict

Sugi Predict / Compounds / SCHEMBL169112

SCHEMBL169112

SCHEMBL169112

O=S(=O)(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 16/20 0.50
▸ CA1 P00915 15/20 0.48
▸ MMP1 P03956 5/20 0.48
▸ MMP2 P08253 5/20 0.48
▸ MMP9 P14780 5/20 0.48
▸ MMP8 P22894 5/20 0.48
▸ MMP13 P45452 5/20 0.48
▸ F2 P00734 4/20 0.43
▸ PRSS1 P07477 4/20 0.43
▸ PRSS2 P07478 4/20 0.43
▸ PRSS3 P35030 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22818194 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL2135574 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL1551243 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL17185508 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL1146134 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL3685584 0.97 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL1395645 0.91 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL1455645 0.91 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL2493205 0.84 CA2 (0.32) CA2CA1MMP1MMP2MMP9
SCHEMBL17185504 0.83 CA2 (0.36) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036566-A Preparation method of perfluoro-butyl sulfonamide 福建邦孚新材料有限公司 2026-05-15 — — CN claimed
CN-119874568-A Synthesis method of perfluoro butyl sulfonyl fluoride 福建三农新材料有限责任公司 2025-04-25 — — CN claimed
US-12258343-B2 Method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-[1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine BAYER AKTIENGESELLSCHAFT (DE) 2025-03-25 — — US claimed
CN-117624583-A Preparation method of Z-type perfluoropolyether anti-fingerprint agent 禾信天成科技（天津）有限公司 2024-03-01 — — CN claimed
EP-3841101-B1 METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE BAYER AG (DE) 2023-05-03 — — EP claimed
CN-110028693-B Preparation method of odor-resistant adsorption pipeline 杭州气味王国科技有限公司 2022-10-28 — — CN claimed
US-20210253573-A1 METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE BAYER AKTIENGESELLSCHAFT (DE) 2021-08-19 — — US claimed
EP-3841101-A1 METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE Bayer Aktiengesellschaft (DE) 2021-06-30 — — EP claimed
CN-106458903-B Method for producing heteroaromatic sulfonamide compound 宇部兴产株式会社 2021-02-05 — — CN claimed
WO-2020039025-A1 METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE BAYER AKTIENGESELLSCHAFT (DE) 2020-02-27 — — WO claimed
EP-1163250-B1 IMPROVED SYNTHESIS OF ¬2.2.1|BICYCLO NUCLEOSIDES EXIQON AS (DK) 2006-07-12 — — EP claimed
CN-1648127-A Imide sulfo N-hydroxy maleopimarate as light acid producing agent and its synthetic method UNIV BEIJING NORMAL (CN) 2005-08-03 — — CN claimed
US-6734291-B2 SULFONYLATION OF A DI(HYDROXYMETHANE)FURO(2,3-D)1,3-DIOXOLE DERIVATIVE WITH A SULFONYL HALIDE EXIQON A/S (DK) 2004-05-11 — — US claimed
US-6639059-B1 Novel synthesis strategy comprising novel key intermediate, (2.2.1)bicyclo nucleosides are produced at least two steps shorter than any previously known strategy; 3-O-aryl-4-C-hydroxymethyl-1,2-O-isopropylidene-alpha-D-ribofuranose EXIQON A/S (DK) 2003-10-28 — — US claimed
US-6599922-B2 Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide (FLECAINIDE) A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.P.A. (IT) 2003-07-29 — — US claimed
US-20030092905-A1 Synthesis of [2.2.1]bicyclo nucleosides EXIQON A/S 2003-05-15 — — US claimed
US-20030032835-A1 Antiarrhythmia agents A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.P.A (IT) 2003-02-13 — — US claimed
EP-1283201-A1 Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-n-(2-piperidyl-methyl)-benzamide (flecanide) A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. (IT) 2003-02-12 — — EP claimed
EP-1163250-A2 IMPROVED SYNTHESIS OF [2.2.1]BICYCLO NUCLEOSIDES Exiqon A/S (DK) 2001-12-19 — — EP claimed
WO-2000056746-A2 IMPROVED SYNTHESIS OF [2.2.1]BICYCLO NUCLEOSIDES EXIQON A/S (US) 2000-09-28 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258343-B2 Method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-[1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine CYP1B1, CYP4B1, CYP1A1 CA2 4874/4885CA1 4881/4885MMP1 4343/4885
US-20030092905-A1 Synthesis of [2.2.1]bicyclo nucleosides NSUN2, RNGTT, RNMT CA2 3694/4885CA1 3530/4885MMP1 4741/4885
US-20210253573-A1 METHOD FOR PREPARING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-[1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAPHTHYRIDINE CYP1B1, CYP4B1, CYP1A1 CA2 4874/4885CA1 4881/4885MMP1 4343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.