Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.75 |
| ▸ | HPGD | P15428 | 7/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.75 |
| ▸ | CASP1 | P29466 | 3/20 | 0.75 |
| ▸ | CASP7 | P55210 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | MYC | P01106 | 1/20 | 0.73 |
| ▸ | MAX | P61244 | 1/20 | 0.73 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718904 | 0.96 | MYC (0.75) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1718655 | 0.91 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1719764 | 0.91 | CHRM4 (0.74) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1718190 | 0.91 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1717548 | 0.89 | MAPT (0.76) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1718546 | 0.89 | MAPT (0.72) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1719119 | 0.88 | HPGD (0.67) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1718061 | 0.88 | TP53 (0.67) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL1718692 | 0.88 | HPGD (0.67) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL20467403 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |