Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275566 | 0.89 | IDO1 (0.55) | IDO1EP300KAT8CYP2D6CA1 | |
| Hydrochloric Acid SCHEMBL31733399 | 0.87 | EP300 (0.56) | IDO1EP300KAT8CYP2D6CA1 | |
| SCHEMBL334379 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL21377269 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL25971643 | 0.81 | CYP1A2 (0.48) | HTR2CCYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL334556 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL29471011 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL29705638 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL1257092 | 0.81 | CA1 (0.55) | IDO1CYP2D6CYP1A2CYP3A4NFKB1 | |
| SCHEMBL9244013 | 0.81 | IDO1 (0.41) | IDO1EP300KAT8HTR2CPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134392-A1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-03-01 | — | — | EP | disclosed |
| WO-2015158313-A1 | SULFONAMIDE DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-22 | — | — | WO | disclosed |