Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744083 | 0.81 | CA1 (0.55) | IDO1CA1CA2CA12CA4 | |
| SCHEMBL17187807 | 0.81 | IDO1 (0.46) | IDO1HDAC4HDAC8EP300KAT8 | |
| SCHEMBL13486819 | 0.81 | LPAR1 (0.42) | IDO1HDAC4HDAC8EP300KAT8 | |
| SCHEMBL357145 | 0.78 | CA1 (0.61) | IDO1EP300KAT8CA1CA2 | |
| SCHEMBL31116611 | 0.78 | CA1 (0.61) | IDO1EP300KAT8CA1CA2 | |
| SCHEMBL31332195 | 0.78 | HTR2A (0.41) | IDO1HDAC4HDAC8EP300KAT8 | |
| SCHEMBL14015293 | 0.78 | TSHR (0.44) | IDO1HDAC4HDAC8EP300KAT8 | |
| SCHEMBL5431939 | 0.75 | PTGS1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL12473426 | 0.74 | CA1 (0.55) | IDO1EP300KAT8CA1CA2 | |
| SCHEMBL13719606 | 0.74 | IDO1 (0.55) | IDO1EP300KAT8CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535682-B1 | Preparation of aryl-substituted olefins | ALBEMARLE CORP (US) | 1995-07-12 | — | — | EP | disclosed |
| EP-0535682-A1 | Preparation of aryl-substituted olefins | ALBEMARLE CORPORATION (US) | 1993-04-07 | — | — | EP | disclosed |