Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590426 | 0.79 | TDP1 (0.44) | ALDH1A1ATMTDP1 | |
| SCHEMBL9937260 | 0.75 | TSHR (0.31) | ALDH1A1TDP1 | |
| SCHEMBL5181617 | 0.75 | TSHR (0.34) | ALDH1A1TDP1 | |
| SCHEMBL11899910 | 0.73 | TTR (0.34) | — | |
| SCHEMBL3238383 | 0.72 | PTPRC (0.41) | ALDH1A1 | |
| SCHEMBL4475271 | 0.67 | — | — | |
| SCHEMBL6806845 | 0.66 | L3MBTL1 (0.48) | ALDH1A1ATMTDP1 | |
| SCHEMBL161280 | 0.66 | — | — | |
| SCHEMBL468092 | 0.66 | — | — | |
| SCHEMBL27502069 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |