SCHEMBL161280

SCHEMBL161280

Cc1[c]ccc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27502069 0.97
SCHEMBL28057914 0.91 ACHE (0.33)
Zinc Chloride SCHEMBL28005895 0.91 ACHE (0.33)
SCHEMBL2012498 0.77 TAAR1 (0.46)
SCHEMBL2014607 0.75 TNKS2 (0.39)
SCHEMBL2013154 0.75 PGR (0.36)
SCHEMBL2053488 0.74 ALDH1A1 (0.44)
SCHEMBL2049821 0.74 CA3 (0.32)
SCHEMBL20240626 0.72 ACHE (0.39)
SCHEMBL1939273 0.72 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2482 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611856-B Piperidine derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-07-05 CN claimed
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US claimed
WO-2024118810-A1 CYCLIC PYRAZOLE DIAMIDE IRE1/XBP1S ACTIVATORS PROTEGO BIOPHARMA, INC. (US) 2024-06-06 WO claimed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN claimed
EP-4345096-A1 PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF Yichang Humanwell Pharmaceutical Co., Ltd. (CN) 2024-04-03 EP claimed
CN-110770214-B Heterocyclic P2X7 antagonists 布雷耶疗法有限公司 2024-03-29 CN claimed
US-20240091303-A1 BIOMARKER-BASED TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND DIABETIC KIDNEY DISEASE GOLDFINCH BIO, INC. 2024-03-21 US claimed
CN-117642402-A Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-03-01 CN claimed
CN-117642389-A Piperidine derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-03-01 CN claimed
EP-3852533-B1 PYRIDAZINONES AND METHODS OF USE THEREOF GOLDFINCH BIO INC (US) 2024-02-28 EP claimed
EP-0121979-B1 AZOLYLMETHYL TETRAHYDROFURAN DERIVATIVES AS PLANT GROWTH REGULATORS AND FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-09-26 EP claimed
EP-0374801-A2 Novel N-sustituted azaheterocyclic carboxylic acids NOVO NORDISK A/S (DK) 1990-06-27 EP claimed
EP-0089100-B1 AZOLYL DERIVATIVES AS FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP claimed
EP-0243983-A2 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-04 EP claimed
US-4636247-A TETRAHYDROFURANYLMETHYLIMIDAZOLES AND -TRIAZOLES, FUNGICIDES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-01-13 US claimed
US-4518415-A PLANT GROWTH REGULATORS, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-21 US claimed
EP-0121979-A2 Azolylmethyl tetrahydrofuran derivatives as plant growth regulators and fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-10-17 EP claimed
EP-0089100-A2 Azolyl derivatives as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-21 EP claimed
US-4335044-A FOR SETTING FRUITS GULF OIL CORPORATION (US) 1982-06-15 US claimed
US-4289527-A APPLYING TO PLANTS, SEEDS, OR SOILS GULF OIL CORPORATION (US) 1981-09-15 US claimed