Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15901974 | 0.73 | LIPG (0.61) | LIPG | |
| SCHEMBL14846340 | 0.73 | LIPG (0.61) | LIPG | |
| SCHEMBL15907566 | 0.70 | LIPG (0.48) | ALDH1A1POLBLIPG | |
| SCHEMBL15952946 | 0.66 | TAS1R3 (0.36) | ACACBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL15952947 | 0.66 | TAS1R3 (0.36) | ACACBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17333776 | 0.66 | CYP1A2 (0.39) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL17340950 | 0.65 | KDM4E (0.39) | KMT2AALDH1A1KDM4EMAPTLIPG | |
| SCHEMBL18832560 | 0.65 | KDM4E (0.39) | KMT2AALDH1A1KDM4EMAPTLIPG | |
| SCHEMBL17928130 | 0.64 | PLAU (0.34) | ACACBKMT2AALDH1A1POLB | |
| SCHEMBL15970577 | 0.63 | HTT (0.45) | KMT2AMEN1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760828-B1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |