Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 11/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | CASP7 | P55210 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2543331 | 0.81 | ALDH1A1 (0.74) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1718168 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1718855 | 0.76 | KDM4E (0.68) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL6030709 | 0.75 | KDM4E (0.69) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1717904 | 0.75 | USP2 (0.75) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1720229 | 0.75 | KDM4E (0.73) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL1717864 | 0.74 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1719162 | 0.74 | KDM4E (0.70) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1719032 | 0.74 | KDM4E (0.79) | ALDH1A1KDM4ETDP1ALOX15MEN1 | |
| SCHEMBL1718037 | 0.74 | KDM4E (0.70) | ALDH1A1KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |