Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719649 | 0.84 | KMT2A (0.58) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1718414 | 0.83 | PTGES (0.65) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1718523 | 0.83 | THRB (0.68) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1718483 | 0.83 | MAPT (0.62) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1718761 | 0.82 | MAPT (0.69) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1719241 | 0.82 | PTGES (0.64) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1718548 | 0.82 | MAPT (0.64) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1719658 | 0.82 | MAPT (0.71) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1719437 | 0.81 | MAPT (0.65) | MAPTRXFP1PTGESCYP1A2CYP3A4 | |
| SCHEMBL1719272 | 0.80 | THRB (0.61) | MAPTRXFP1PTGESCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |