Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718369 | 0.86 | RXFP1 (0.59) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL1719380 | 0.86 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1718522 | 0.85 | KMT2A (0.67) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL3714389 | 0.84 | KDM4E (0.72) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1718497 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1717837 | 0.80 | KMT2A (0.65) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1718942 | 0.80 | MAPT (0.64) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1719355 | 0.80 | ALDH1A1 (0.98) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL4210744 | 0.79 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL1718304 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |