Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.65 |
| ▸ | FLT3 | P36888 | 9/20 | 0.65 |
| ▸ | FLT4 | P35916 | 9/20 | 0.65 |
| ▸ | CSF1R | P07333 | 5/20 | 0.65 |
| ▸ | KDR | P35968 | 8/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099153 | 0.94 | PDGFRB (0.59) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4185538 | 0.89 | PDGFRB (0.51) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL1099216 | 0.86 | PDGFRB (0.66) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL1097598 | 0.86 | PDGFRB (0.65) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL4669695 | 0.85 | KDR (0.74) | PDGFRBFLT4CSF1RKDRPDGFRA | |
| SCHEMBL1099731 | 0.82 | KDR (0.54) | PDGFRBFLT4CSF1RKDRPDGFRA | |
| SCHEMBL1099936 | 0.82 | KDR (0.54) | PDGFRBFLT4CSF1RKDRPDGFRA | |
| SCHEMBL4371744 | 0.82 | MET (0.77) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL20788539 | 0.82 | KMT2A (0.64) | PDGFRBFLT3FLT4CSF1RKDR | |
| SCHEMBL1098052 | 0.81 | PDGFRB (0.60) | PDGFRBFLT3FLT4CSF1RKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802591-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-01-11 | — | — | EP | claimed |