Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1636823 | 0.93 | SMN1; SMN2 (0.45) | TERTPOLBSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL1719827 | 0.83 | POLB (0.45) | TERTPOLBSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL1636865 | 0.83 | KDM4E (0.41) | POLBSMN1; SMN2NPC1RAB9AKDM4E | |
| Trifluoroacetic Acid SCHEMBL1636097 | 0.77 | SMN1; SMN2 (0.45) | TERTPOLBSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL1635260 | 0.74 | RAB9A (0.44) | POLBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL20362084 | 0.72 | MAPT (0.52) | POLBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3274206 | 0.71 | MEN1 (0.57) | POLBSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL3275818 | 0.69 | MEN1 (0.53) | POLBSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL1635346 | 0.68 | KDM4E (0.41) | POLBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5675501 | 0.68 | KDM4E (0.77) | POLBSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786828-B1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2012-01-11 | — | — | EP | disclosed |
| EP-1786828-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006030119-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | bioMérieux (FR) | 2006-03-23 | — | — | WO | disclosed |