Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327418 | 0.88 | CASP3 (0.57) | MEN1KMT2ANPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL125553 | 0.87 | CASP3 (0.56) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3275818 | 0.86 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL14347198 | 0.85 | RAB9A (0.62) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL18709101 | 0.82 | POLB (0.65) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3274811 | 0.79 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL1108169 | 0.79 | NPC1 (0.66) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL12534073 | 0.79 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL2609273 | 0.77 | MEN1 (0.62) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3275224 | 0.76 | KMT2A (0.62) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695930-B2 | Method for the detection, identification and/or quantification of microoganisms with peptidase activity using phenoxazinone derivatives as enzyme substrates | BIOMERIEUX (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20080286820-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-11-20 | — | — | US | disclosed |
| US-7420054-B2 | Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-09-02 | — | — | US | disclosed |
| EP-1625117-B1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2008-01-09 | — | — | EP | disclosed |
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2006-06-08 | — | — | US | disclosed |
| EP-1625117-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004101536-A1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | PEPD, CTRL, PM20D2 | MEN1 2241/4885KMT2A 3619/4885NPC1 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.