Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775505 | 1.00 | AGXT (0.46) | AGXTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL17345718 | 0.90 | AGXT (0.50) | AGXTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL19007222 | 0.84 | LMNA (0.55) | AGXTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL16614038 | 0.84 | ACP3 (0.50) | CASRSIGMAR1ACP3SMN1; SMN2MEN1 | |
| SCHEMBL17468631 | 0.84 | ACP3 (0.50) | CASRSIGMAR1ACP3SMN1; SMN2MEN1 | |
| SCHEMBL17266295 | 0.83 | MAOB (0.46) | CASRSIGMAR1ACP3SMN1; SMN2MEN1 | |
| SCHEMBL26324335 | 0.82 | CASR (0.47) | AGXTLMNAALDH1A1MAPK1HTT | |
| SCHEMBL18977995 | 0.78 | SLC6A2 (0.43) | LMNAALDH1A1MAPK1CASRSMN1; SMN2 | |
| SCHEMBL17266149 | 0.77 | MAOA (0.43) | AGXTALDH1A1CASRAOC3 | |
| SCHEMBL18977561 | 0.76 | LMNA (0.37) | LMNAALDH1A1MAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015160224-A1 | MULTI-COMPONENT HOST MATERIAL AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2015-10-22 | — | — | WO | disclosed |