Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718865 | 0.97 | PTGES (0.69) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1718426 | 0.92 | MAPT (0.62) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1719548 | 0.92 | PTGES (0.64) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1718414 | 0.91 | PTGES (0.65) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1717929 | 0.91 | PTGES (0.64) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1718612 | 0.90 | MAPT (0.64) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1718588 | 0.90 | PTGES (0.66) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1719241 | 0.90 | PTGES (0.64) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1719000 | 0.89 | PTGES (0.58) | PTGESMAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1717910 | 0.88 | PTGES (0.61) | PTGESMAPTGAAL3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |