Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719998 | 0.93 | USP2 (0.53) | USP2MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1718886 | 0.91 | USP2 (0.51) | USP2MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1718562 | 0.84 | ALDH1A1 (0.58) | USP2MAPTGAAL3MBTL1RXFP1 | |
| SCHEMBL1718881 | 0.84 | USP2 (0.60) | USP2MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1719141 | 0.81 | MAPT (0.64) | USP2MAPTGAAL3MBTL1PTGES | |
| SCHEMBL1718620 | 0.81 | ALDH1A1 (0.59) | MAPTGAAL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL1718686 | 0.81 | ALDH1A1 (0.58) | USP2MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1719409 | 0.81 | MAPT (0.69) | USP2MAPTGAAL3MBTL1PTGES | |
| SCHEMBL1719255 | 0.81 | ALDH1A1 (0.57) | USP2MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL1718176 | 0.81 | ALDH1A1 (0.57) | USP2MAPTGAAL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |