SCHEMBL17197409 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN11	Q06124	4/20	0.47

▸	TSHR	P16473	3/20	0.44

▸	HSD17B10	Q99714	1/20	0.44

▸	S1PR3	Q99500	1/20	0.44

▸	PTPN1	P18031	1/20	0.41

▸	PTPN6	P29350	1/20	0.41

▸	KMT2A	Q03164	1/20	0.41

▸	HTT	P42858	1/20	0.40

▸	PLA2G2A	P14555	1/20	0.40

▸	TP53	P04637	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7760951	0.96	KMT2A (0.44)	PTPN11TSHRHSD17B10KMT2A
SCHEMBL7759459	0.96	KMT2A (0.44)	PTPN11TSHRHSD17B10KMT2A
SCHEMBL18417238	0.90	KMT2A (0.54)	TSHRKMT2A
SCHEMBL25428188	0.90	KMT2A (0.46)	TSHRHSD17B10KMT2A
SCHEMBL19821462	0.86	MEN1 (0.49)	TSHRKMT2AHTT
SCHEMBL19821463	0.86	MEN1 (0.49)	TSHRKMT2AHTT
SCHEMBL668867	0.83	TSHR (0.54)	TSHRHSD17B10KMT2ATP53
SCHEMBL8106327	0.81	PTPN11 (0.37)	PTPN11TSHRHSD17B10S1PR3PTPN1
SCHEMBL8100384	0.81	PTPN11 (0.37)	PTPN11TSHRHSD17B10S1PR3PTPN1
SCHEMBL7754584	0.81	KMT2A (0.47)	TSHRKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015159098-A1	FLUOROALKYLFLUORENE DERIVATIVES	LOMOX LIMITED (GB)	2015-10-22	—	—	WO	disclosed