Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760951 | 1.00 | KMT2A (0.44) | KMT2ATSHRCYP4F2CYP4A11CA12 | |
| SCHEMBL17197409 | 0.96 | PTPN11 (0.47) | KMT2ATSHRPTPN11HSD17B10 | |
| SCHEMBL18417238 | 0.94 | KMT2A (0.54) | KMT2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL25428188 | 0.94 | KMT2A (0.46) | KMT2ATSHRCYP4F2CYP4A11CA12 | |
| SCHEMBL19821463 | 0.87 | MEN1 (0.49) | KMT2ATSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL19821462 | 0.87 | MEN1 (0.49) | KMT2ATSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL668867 | 0.87 | TSHR (0.54) | KMT2ATSHRLMNAALDH1A1CYP3A4 | |
| SCHEMBL7759780 | 0.84 | KMT2A (0.47) | KMT2ATSHRCA12CA1CA2 | |
| SCHEMBL7754584 | 0.84 | KMT2A (0.47) | KMT2ATSHRCA12CA1CA2 | |
| SCHEMBL18758110 | 0.84 | KMT2A (0.42) | KMT2APTPN11ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10923662-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
| EP-3131898-B1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LTD (GB) | 2020-03-18 | — | — | EP | disclosed |
| US-10084137-B2 | Fluoroalkylfluorene derivatives | LOMOX LIMITED (GB) | 2018-09-25 | — | — | US | disclosed |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2018-09-13 | — | — | US | disclosed |
| EP-3131898-A1 | FLUOROALKYLFLUORENE DERIVATIVES | Lomox Limited (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2017-02-02 | — | — | US | disclosed |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2017-02-02 | — | — | US | disclosed |
| WO-2015159098-A1 | FLUOROALKYLFLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2015-10-22 | — | — | WO | disclosed |
| EP-0754675-B1 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 2001-03-21 | — | — | EP | disclosed |
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |
| EP-0754675-A2 | Dental materials on basis of liquid crystal monomers | IVOCLAR AG (LI) | 1997-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10084137-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | KMT2A 2324/4885TSHR 3720/4885CYP4F2 202/4885 |
| US-20170033290-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | KMT2A 2324/4885TSHR 3720/4885CYP4F2 202/4885 |
| US-10923662-B2 | Fluoroalkylfluorene derivatives | FLNB, AFF2, EFHD2 | KMT2A 2324/4885TSHR 3720/4885CYP4F2 202/4885 |
| US-20180261771-A1 | FLUOROALKYLFLUORENE DERIVATIVES | FLNB, AFF2, EFHD2 | KMT2A 2324/4885TSHR 3720/4885CYP4F2 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.