Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106327 | 1.00 | PTPN11 (0.37) | PTPN11ALDH1A1HPGDKDM4ECYP3A4 | |
| SCHEMBL668869 | 0.91 | PTPN11 (0.41) | PTPN11ALDH1A1HPGDS1PR3TSHR | |
| SCHEMBL8106646 | 0.90 | CYSLTR2 (0.35) | ALDH1A1HPGDKDM4ECYP3A4CYP2C9 | |
| SCHEMBL8102311 | 0.90 | CYSLTR2 (0.35) | ALDH1A1HPGDKDM4ECYP3A4CYP2C9 | |
| SCHEMBL17197409 | 0.81 | PTPN11 (0.47) | PTPN11S1PR3TSHRHSD17B10PTPN1 | |
| SCHEMBL7760951 | 0.80 | KMT2A (0.44) | PTPN11ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL7759459 | 0.80 | KMT2A (0.44) | PTPN11ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8106324 | 0.79 | PLA2G2A (0.41) | TSHRPLA2G2A | |
| SCHEMBL8100381 | 0.79 | PLA2G2A (0.41) | TSHRPLA2G2A | |
| SCHEMBL5843785 | 0.78 | EGFR (0.36) | ALDH1A1HPGDKDM4ECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |