Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 7/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17171865 | 0.88 | CNR2 (0.35) | CYP3A4CYP3A5CYP19A1LMNA | |
| SCHEMBL17171923 | 0.86 | ABL1 (0.42) | CYP3A4CYP3A5CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL17171915 | 0.84 | CYP3A4 (0.50) | CYP3A4CYP3A5CYP19A1LMNA | |
| SCHEMBL17171925 | 0.84 | CYP19A1 (0.39) | CYP3A4CYP3A5CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL17171930 | 0.83 | KIF11 (0.50) | CYP3A4CYP3A5CYP19A1 | |
| SCHEMBL17171924 | 0.83 | CYP19A1 (0.40) | CYP3A4CYP3A5CYP19A1 | |
| SCHEMBL17199260 | 0.82 | CYP19A1 (0.45) | CYP3A4CYP3A5CYP19A1 | |
| SCHEMBL17171922 | 0.80 | CYP19A1 (0.41) | CYP3A4CYP3A5CYP19A1 | |
| SCHEMBL17172223 | 0.80 | CYP3A4 (0.43) | CYP3A4CYP3A5CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL17171926 | 0.80 | CYP11B2 (0.46) | CYP3A4CYP3A5CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| WO-2015160664-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | CYP3A4 89/4885CYP3A5 94/4885CYP19A1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.