Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720133 | 0.91 | RXFP1 (0.71) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1719295 | 0.91 | RXFP1 (0.65) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1718483 | 0.91 | MAPT (0.62) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1719938 | 0.89 | RXFP1 (0.61) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1719793 | 0.89 | RXFP1 (0.63) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1717682 | 0.87 | RXFP1 (0.67) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1719212 | 0.86 | RXFP1 (0.62) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1719241 | 0.86 | PTGES (0.64) | MAPTRXFP1THRBUSP2PTGES | |
| SCHEMBL1718853 | 0.86 | KMT2A (0.62) | MAPTRXFP1POLBMEN1ALDH1A1 | |
| SCHEMBL1719731 | 0.85 | RXFP1 (0.61) | MAPTRXFP1THRBUSP2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |