Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694204 | 0.97 | MAPK1 (0.42) | ALDH1A1HIF1AMAPK1GPR183USP2 | |
| SCHEMBL653419 | 0.86 | USP2 (0.48) | ALDH1A1MAPK1USP2KITPKM | |
| SCHEMBL653321 | 0.85 | HSD11B1 (0.43) | GPR183HRH4KMT2A | |
| SCHEMBL654247 | 0.79 | HRH4 (0.48) | KITHRH4 | |
| SCHEMBL654044 | 0.74 | GFER (0.53) | ALDH1A1GPR183KITHRH4MEN1 | |
| SCHEMBL1721326 | 0.71 | GFER (0.49) | ALDH1A1GPR183KITHRH4MEN1 | |
| SCHEMBL654187 | 0.70 | PI4KB (0.48) | ALDH1A1MAPK1USP2MEN1KMT2A | |
| SCHEMBL654776 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KITKMT2A | |
| SCHEMBL653903 | 0.70 | HSP90AA1 (0.51) | KITHRH4MEN1KMT2A | |
| SCHEMBL654230 | 0.69 | HRH4 (0.44) | ALDH1A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |