Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL29234087 | 0.88 | MAPT (0.44) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL2489430 | 0.86 | ALDH1A1 (0.39) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL29234278 | 0.85 | MAPT (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL10735716 | 0.85 | MAPT (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL29234186 | 0.85 | MAPT (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL11800024 | 0.85 | MAPT (0.47) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL17199874 | 0.84 | CYP1A2 (0.34) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| Trolamine SCHEMBL28230333 | 0.83 | ALDH1A1 (0.37) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL97470 | 0.79 | MAPT (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A | |
| SCHEMBL8990 | 0.79 | MAPT (0.42) | CYP1A2CYP2C9HPGDMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937075-A1 | SKIN BARRIER PROTECTIVE INGREDIENT AND COSMETIC AND/OR DERMATOLOGICAL FORMULATION CONTAINING THE SAME | Botica Comercial Farmacêutica Ltda. (BR) | 2015-10-28 | — | — | EP | disclosed |