Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL28230333 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL11800024 | 0.87 | MAPT (0.47) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| SCHEMBL442289 | 0.87 | CYP1A2 (0.39) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL17199873 | 0.86 | CYP1A2 (0.37) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| SCHEMBL18067187 | 0.85 | CYP1A2 (0.38) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL27316942 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL1092043 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL5708445 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL29234087 | 0.84 | MAPT (0.44) | ALDH1A1TSHRMAPTCYP1A2CYP2C9 | |
| Trolamine SCHEMBL10392738 | 0.83 | DNM1 (0.59) | ALDH1A1TSHRHSD17B10SMN1; SMN2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1057598-A | The froth flotation of silica or siliceous gangue | DOW CHEMICAL CO (US) | 1992-01-08 | — | — | CN | claimed |
| CN-110325180-A | Liquid preparation for percutaneous absorption containing memantine | 株式会社梅德瑞科思 | 2019-10-11 | — | — | CN | disclosed |
| US-8034123-B2 | Boosting cleaning power of detergents by means of a polymer | HENKEL AG & CO., KGAA (DE) | 2011-10-11 | — | — | US | disclosed |
| US-8012267-B2 | Machine dishwashing method with separately metered liquid cleaning agents | HENKEL AG & CO. KGAA (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20090280345-A1 | COMPOSITIONS FOR USE IN TREATING ORGANIC SUBSTANCES | MATTERSMITHS HOLDINGS LIMITED (NZ) | 2009-11-12 | — | — | US | disclosed |
| EP-1866133-A4 | COMPOSITIONS FOR USE IN TREATING ORGANIC SUBSTANCES | MATTERSMITHS TECHNOLOGIES LTD (NZ) | 2009-08-12 | — | — | EP | disclosed |
| EP-1866133-A1 | COMPOSITIONS FOR USE IN TREATING ORGANIC SUBSTANCES | Mattersmiths Holdings Limited (NZ) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006091113-A1 | COMPOSITIONS FOR USE IN TREATING ORGANIC SUBSTANCES | MATTERSMITHS HOLDINGS LIMITED, (NZ) | 2006-08-31 | — | — | WO | disclosed |