Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17136567 | 0.92 | MMP8 (0.46) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136453 | 0.91 | MMP8 (0.50) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136377 | 0.91 | MMP8 (0.56) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17199890 | 0.90 | MMP8 (0.53) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136446 | 0.90 | MMP8 (0.48) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17199916 | 0.90 | MEN1 (0.51) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136455 | 0.90 | MMP8 (0.48) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17199924 | 0.89 | MMP8 (0.49) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136573 | 0.88 | HCRTR1 (0.56) | MMP8MMP12MMP13ALDH1A1TRPA1 | |
| SCHEMBL17136492 | 0.88 | TRPA1 (0.53) | MMP8MMP12MMP13ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937335-A1 | HETEROCYCLIC AMIDE DERIVATIVE, AND MEDICINE CONTAINING SAME | Ajinomoto Co., Inc. (JP) | 2015-10-28 | — | — | EP | disclosed |