Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17136569 | 0.94 | TRPA1 (0.52) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17199902 | 0.93 | TRPA1 (0.58) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17136492 | 0.93 | TRPA1 (0.53) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17199898 | 0.91 | TRPA1 (0.61) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17136474 | 0.91 | TRPA1 (0.61) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17199887 | 0.89 | TRPA1 (0.56) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17136454 | 0.89 | TRPA1 (0.55) | TRPA1MMP8MMP12MMP13HCRTR1 | |
| SCHEMBL17199901 | 0.88 | TRPA1 (0.53) | TRPA1MMP1ADAM17MMP8MMP12 | |
| SCHEMBL17136565 | 0.87 | TRPA1 (0.54) | TRPA1MMP8MMP12MMP13HCRTR1 | |
| SCHEMBL17136379 | 0.87 | TRPA1 (0.52) | TRPA1MMP8MMP12MMP13HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937335-A1 | HETEROCYCLIC AMIDE DERIVATIVE, AND MEDICINE CONTAINING SAME | Ajinomoto Co., Inc. (JP) | 2015-10-28 | — | — | EP | disclosed |