Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 10/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2732706 | 0.99 | MAPK8 (0.45) | MAPK8LOXL2MAPK9HDAC6KDM4E | |
| SCHEMBL2730661 | 0.88 | GAA (0.47) | HDAC6ALDH1A1HPGDMAPK10 | |
| SCHEMBL27928721 | 0.85 | MAPK8 (0.46) | MAPK8LOXL2MAPK9HDAC6KDM4E | |
| SCHEMBL2730314 | 0.85 | CCR2 (0.41) | MAPK8MAPK9HDAC6F10PLA2G2A | |
| Hydrochloric Acid SCHEMBL2731134 | 0.84 | CCR2 (0.41) | MAPK8MAPK9HDAC6ALDH1A1F10 | |
| SCHEMBL2731042 | 0.82 | LOXL2 (0.42) | MAPK8LOXL2MAPK9ALDH1A1MAPK10 | |
| SCHEMBL2730596 | 0.82 | MAPK8 (0.39) | MAPK8MAPK9HDAC6KDM4EALDH1A1 | |
| SCHEMBL2731177 | 0.81 | MAPK8 (0.44) | MAPK8MAPK9KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2730594 | 0.81 | MAPK8 (0.39) | MAPK8MAPK9HDAC6KDM4EALDH1A1 | |
| SCHEMBL2730493 | 0.79 | MAPK8 (0.42) | MAPK8MAPK9KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | disclosed |