Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17200012 | 0.86 | PPARA (0.41) | RAB9AL3MBTL1PPARANPC1SMN1; SMN2 | |
| SCHEMBL9525312 | 0.84 | EPHX2 (0.38) | EPHX2RAB9ATDP1L3MBTL1PPARA | |
| SCHEMBL3723489 | 0.76 | HCAR2 (0.52) | RAB9AL3MBTL1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL22432012 | 0.75 | — | — | |
| SCHEMBL7510232 | 0.73 | SMPD1 (0.45) | KMT2ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL185760 | 0.73 | ALDH1A1 (0.39) | TDP1KMT2AHCAR2KDM4EALDH1A1 | |
| SCHEMBL8986681 | 0.72 | ALDH1A1 (0.31) | HCAR2ALDH1A1 | |
| SCHEMBL597064 | 0.72 | HCAR2 (0.57) | EPHX2RAB9ATDP1L3MBTL1PPARA | |
| SCHEMBL11144537 | 0.72 | ALDH1A1 (0.34) | HCAR2ALDH1A1 | |
| SCHEMBL186457 | 0.72 | TSHR (0.32) | HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |