Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289038 | 0.81 | NPC1 (0.43) | GAAEDNRBEDNRACYP1A2CYP2C9 | |
| SCHEMBL3742998 | 0.81 | CYP1A2 (0.37) | GAANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2289383 | 0.81 | NPSR1 (0.47) | ALDH1A1GAANPSR1CYP1A2CYP2C9 | |
| SCHEMBL3739810 | 0.81 | NPC1 (0.37) | ALDH1A1GAANPSR1CYP1A2CYP2C9 | |
| SCHEMBL7111143 | 0.80 | MTNR1A (0.39) | HSD17B10ALOX15 | |
| SCHEMBL1720657 | 0.77 | KDM4E (0.41) | ALDH1A1TP53KDM4ENPC1RAB9A | |
| SCHEMBL10181023 | 0.77 | CYP1A2 (0.53) | ALDH1A1CYP1A2KDM4ESMN1; SMN2CTSA | |
| SCHEMBL2283859 | 0.76 | NPSR1 (0.44) | ALDH1A1GAAMAPTNPSR1CYP1A2 | |
| SCHEMBL2292844 | 0.76 | CYP1A2 (0.40) | ALDH1A1GAAMAPTNPSR1EDNRB | |
| SCHEMBL2288581 | 0.75 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10MAPTNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334968-B1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7820861-B2 | chemical intermediate for a sulfonanilide of 4,6-dimethoxypyrmidine derivative herbicide | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7531654-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7521555-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7504503-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| EP-2025665-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7271263-B2 | Process for production of substituted aniline compound | IHARA CHEMICAL INDUSTRY, CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20070213561-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213533-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213532-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20060281765-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| US-20040034251-A1 | Process for production of substituted aniline compound | 1HARA CHEMICAL INDUSTRY CO., LT.D. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1334968-A1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034251-A1 | Process for production of substituted aniline compound | NAT1, CBR3, AADAC | ALDH1A1 189/4885HSD17B10 99/4885CFTR 1523/4885 |
| US-20070213561-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | ALDH1A1 207/4885HSD17B10 72/4885CFTR 1951/4885 |
| US-20060281765-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | ALDH1A1 207/4885HSD17B10 72/4885CFTR 1951/4885 |
| US-20070213532-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | ALDH1A1 207/4885HSD17B10 72/4885CFTR 1951/4885 |
| US-20070213533-A1 | Process for producing substituted aniline compound | AADAC, NAT1, CBR3 | ALDH1A1 212/4885HSD17B10 92/4885CFTR 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.