Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224731 | 0.93 | MAPT (0.59) | LMNAMAPTABCB11MAPK1ATM | |
| SCHEMBL11157443 | 0.93 | MAPT (0.59) | LMNAMAPTABCB11MAPK1ATM | |
| SCHEMBL15194530 | 0.92 | LMNA (0.55) | LMNAMAPTABCB11MAPK1ATM | |
| SCHEMBL11070268 | 0.86 | ABCB11 (0.53) | LMNAMAPTABCB11MAPK1ATM | |
| Cyclopentane SCHEMBL11247040 | 0.85 | LMNA (0.48) | LMNAMAPTABCB11MAPK1ATM | |
| SCHEMBL11073407 | 0.84 | ABCB11 (0.49) | LMNAMAPTABCB11MAPK1 | |
| SCHEMBL14967401 | 0.83 | LMNA (0.46) | LMNAMAPTABCB11MAPK1ATM | |
| SCHEMBL11069904 | 0.83 | ABCB11 (0.48) | LMNAMAPTABCB11MAPK1 | |
| SCHEMBL11076754 | 0.83 | ABCB11 (0.51) | LMNAMAPTABCB11MAPK1 | |
| SCHEMBL11066327 | 0.83 | ABCB11 (0.51) | LMNAMAPTABCB11MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307640-A1 | POLYBUTADIENE HAVING EPOXY GROUPS | EVONIK DEGUSSA GMBH (DE) | 2015-10-29 | — | — | US | disclosed |