Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910508 | 0.70 | MAPT (0.47) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL3076780 | 0.66 | MAOB (0.33) | MAPTTSHRKDM4EGAAHTT | |
| SCHEMBL1096341 | 0.66 | MAPT (0.41) | MAPTTSHRKDM4EGAAHTT | |
| SCHEMBL910353 | 0.66 | ITGB2 (0.33) | MAPTTSHRALDH1A1KDM4EGAA | |
| SCHEMBL2205252 | 0.66 | ALDH1A1 (0.35) | MAPTTSHRALDH1A1KDM4EGAA | |
| SCHEMBL20563965 | 0.62 | TSHR (0.32) | TSHR | |
| SCHEMBL20563658 | 0.62 | ALDH1A1 (0.32) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20562890 | 0.62 | PKM (0.32) | MAPTTSHRALDH1A1KDM4EGAA | |
| SCHEMBL4524447 | 0.62 | KDM4E (0.35) | MAPTTSHRALDH1A1KDM4EGAA | |
| SCHEMBL27382541 | 0.61 | ITGB2 (0.53) | MAPTTSHRALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |