Diatrizoic Acid

Diatrizoic Acid

SCHEMBL17201714

CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I.CCCC[N+](CCCC)(CCCC)CCCC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
SLC22A1 O15245 3/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC22A2 O15244 1/20 0.32
PLK1 P53350 3/20 0.32
PLK3 Q9H4B4 2/20 0.32
TRPV1 Q8NER1 1/20 0.31
PLA2G2C Q5R387 1/20 0.31
BID P55957 1/20 0.31
BCL2L1 Q07817 1/20 0.31
MCL1 Q07820 1/20 0.31
BAK1 Q16611 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diatrizoic Acid SCHEMBL8859575 0.85 LMNA (0.55) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL8508 0.83 LMNA (0.67) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL6362397 0.82 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL8053758 0.82 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL5960726 0.82 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1
Diatrizoic Acid SCHEMBL3974126 0.82 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL8752140 0.80 LMNA (0.67) LMNASMN1; SMN2TSHRMAPK1
Hydrochloric Acid SCHEMBL8089018 0.78 LMNA (0.65) LMNASMN1; SMN2TSHRMAPK1
SCHEMBL11588043 0.76 LMNA (0.59) LMNASMN1; SMN2TSHRMAPK1
Ioxotrizoic Acid SCHEMBL37821 0.76 LMNA (0.59) LMNASMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240091403-A1 PARTICLES MICROVENTION, INC. 2024-03-21 US disclosed
US-11857694-B2 Particles MICROVENTION, INC. (US) 2024-01-02 US disclosed
US-20220176012-A1 PARTICLES MICROVENTION, INC. 2022-06-09 US disclosed
US-11285240-B2 Particles MICROVENTION, INC. (US) 2022-03-29 US disclosed
US-10946100-B2 Polymers including active agents MICROVENTION, INC. (US) 2021-03-16 US disclosed
US-20200397942-A1 PARTICLES MICROVENTION, INC. 2020-12-24 US disclosed
US-10792390-B2 Particles MICROVENTION, INC. (US) 2020-10-06 US disclosed
US-20200121824-A1 PARTICLES MICROVENTION, INC. 2020-04-23 US disclosed
US-10543295-B2 Particles MICROVENTION, INC. (US) 2020-01-28 US disclosed
US-20190343982-A1 PARTICLES MICROVENTION, INC. 2019-11-14 US disclosed
US-10226533-B2 Polymer filaments including pharmaceutical agents and delivering same MICROVENTION, INC. (US) 2019-03-12 US disclosed
EP-3137124-B1 POLYMERS INCLUDING ACTIVE AGENTS MICROVENTION INC (US) 2019-01-09 EP disclosed
US-10155064-B2 Particles MICROVENTION, INC. (US) 2018-12-18 US disclosed
US-20180147317-A1 PARTICLES MICROVENTION, INC. 2018-05-31 US disclosed
US-9907880-B2 Particles MICROVENTION, INC. 2018-03-06 US disclosed
EP-3137124-A1 POLYMERS INCLUDING ACTIVE AGENTS Microvention, Inc. (US) 2017-03-08 EP disclosed
WO-2016154592-A1 EMBIOLIC PARTICLES MICROVENTION, INC. (US) 2016-09-29 WO disclosed
US-20160279282-A1 PARTICLES MICROVENTION, INC. 2016-09-29 US disclosed
WO-2015167752-A1 POLYMERS INCLUDING ACTIVE AGENTS MICROVENTION, INC. (US) 2015-11-05 WO disclosed
US-20150306227-A1 POLYMERS INCLUDING ACTIVE AGENTS MICROVENTION, INC. 2015-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10226533-B2 Polymer filaments including pharmaceutical agents and delivering same MFAP1, ACTB, MAPT LMNA 243/4885SMN1; SMN2 494/4885SLC22A1 4181/4885
US-10946100-B2 Polymers including active agents MFAP1, VCL, ACTB LMNA 199/4885SMN1; SMN2 1078/4885SLC22A1 4647/4885
US-20150306227-A1 POLYMERS INCLUDING ACTIVE AGENTS MFAP1, VCL, ACTB LMNA 199/4885SMN1; SMN2 1078/4885SLC22A1 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.