Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 4/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539056 | 1.00 | MAP3K12 (0.47) | MAP3K12DYRK1APIM1PIM3PIM2 | |
| SCHEMBL17210369 | 1.00 | MAP3K12 (0.47) | MAP3K12DYRK1APIM1PIM3PIM2 | |
| SCHEMBL17210359 | 0.96 | MAP3K12 (0.43) | MAP3K12DYRK1APIM1PIM3PIM2 | |
| SCHEMBL17201937 | 0.86 | DYRK1A (0.45) | MAP3K12DYRK1APIM1PIM3PIM2 | |
| SCHEMBL17201952 | 0.83 | DYRK1A (0.42) | MAP3K12DYRK1APIM1PIM3PIM2 | |
| SCHEMBL24942475 | 0.82 | DYRK1A (0.51) | MAP3K12DYRK1ASMPD3PBRM1LRRK2 | |
| SCHEMBL24942471 | 0.82 | DYRK1A (0.51) | MAP3K12DYRK1ASMPD3PBRM1LRRK2 | |
| SCHEMBL17210340 | 0.81 | TRPA1 (0.49) | PIK3CAMTOR | |
| SCHEMBL17202009 | 0.81 | TRPA1 (0.49) | PIK3CAMTOR | |
| SCHEMBL17205369 | 0.81 | TRPA1 (0.49) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134410-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | Hydra Biosciences, Inc. (US) | 2017-03-01 | — | — | EP | disclosed |
| WO-2015164643-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2015-10-29 | — | — | WO | disclosed |