Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 18/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720374 | 0.70 | STIM1 (0.43) | CCNT1STIM1ORAI1 | |
| Hydrochloric Acid SCHEMBL17186536 | 0.65 | PNP (0.58) | — | |
| SCHEMBL2686641 | 0.65 | ADORA2B (0.49) | CCNT1STIM1ORAI1 | |
| SCHEMBL23860286 | 0.64 | TLR7 (0.34) | — | |
| SCHEMBL1720832 | 0.64 | ADORA2B (0.37) | — | |
| Hydrochloric Acid SCHEMBL17186548 | 0.63 | PNP (0.54) | — | |
| SCHEMBL9234446 | 0.63 | PNP (0.72) | — | |
| SCHEMBL27304412 | 0.61 | NTRK1 (0.61) | CCNT1STIM1ORAI1 | |
| SCHEMBL1867614 | 0.61 | HCAR2 (0.51) | — | |
| SCHEMBL1192525 | 0.60 | BRAF (0.53) | CCNT1STIM1ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405917-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | Advinus Therapeutics Private Limited (IN) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103547-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2010-09-16 | — | — | WO | disclosed |