Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989534 | 0.78 | HSP90AB1 (0.44) | NPC1RAB9AS1PR2ALDH1A1LMNA | |
| SCHEMBL1719917 | 0.76 | HTT (0.67) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL24738809 | 0.75 | KDM4E (0.50) | RAB9AHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11000782 | 0.75 | ALDH1A1 (0.34) | HTTS1PR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6034188 | 0.74 | ALDH1A1 (0.41) | S1PR2ALDH1A1LMNACYP3A4KDM4E | |
| SCHEMBL9460630 | 0.72 | HTT (0.52) | HTTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL1720666 | 0.71 | CYP1A2 (0.52) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL16503642 | 0.70 | SMN1; SMN2 (0.42) | NPC1RAB9AHTTS1PR2ALDH1A1 | |
| SCHEMBL9461180 | 0.70 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL21434181 | 0.69 | RECQL (0.38) | HTTS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334968-B1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7820861-B2 | chemical intermediate for a sulfonanilide of 4,6-dimethoxypyrmidine derivative herbicide | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| EP-2025665-B1 | Process for producing substituted aniline compound | IHARA CHEMICAL IND CO (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-7531654-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7521555-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7504503-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| EP-2025665-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7271263-B2 | Process for production of substituted aniline compound | IHARA CHEMICAL INDUSTRY, CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20070213561-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213532-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213533-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20060281765-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| US-20040034251-A1 | Process for production of substituted aniline compound | 1HARA CHEMICAL INDUSTRY CO., LT.D. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1334968-A1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034251-A1 | Process for production of substituted aniline compound | NAT1, CBR3, AADAC | NPC1 2795/4885RAB9A 2192/4885HTT 2412/4885 |
| US-20070213561-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | NPC1 3420/4885RAB9A 3060/4885HTT 1962/4885 |
| US-20060281765-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | NPC1 3420/4885RAB9A 3060/4885HTT 1962/4885 |
| US-20070213532-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | NPC1 3420/4885RAB9A 3060/4885HTT 1962/4885 |
| US-20070213533-A1 | Process for producing substituted aniline compound | AADAC, NAT1, CBR3 | NPC1 3387/4885RAB9A 3398/4885HTT 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.